In critical fields such as pharmaceuticals, chemicals, and food testing, the mobile phase, as the core solvent system in high-performance liquid chromatography, requires precise preparation for successful experiments. However, traditional manual operations are not only inefficient but also prone to significant error risks. Today, Dark Laboratory is revolutionizing this critical area with its fully automated and unmanned technology. The mobile phase preparation workstation launched by Beijing Dynaflow Experimental Technology Co., Ltd. is a pioneer in this transformation.

1. Dark Laboratory: The Smart Core of Mobile Phase Preparation

The core competitiveness of Dark Laboratory lies in its concept of "unmanned operation" and "full-process closed-loop control." The mobile phase preparation workstation achieves this goal through a series of precisely designed modules.       

Hardware System  The workstation is equipped with a high-precision collaborative robot, which uses precision fixtures to accurately perform tasks such as opening and closing bottle caps, transferring storage bottles, and powder feeding, with a repeat positioning accuracy of ±0.02mm. The workstation also integrates ultrasonic degassing devices, pH adjustment modules, powder weighing and feeding systems, and filtration units. All operations are coordinated by the robot, and the prepared mobile phase is automatically transferred to designated areas using AGVs, achieving a high level of automation and intelligence.

Software and Monitoring System  The workstation provides real-time status visualization. The main interface clearly displays robot simulation, equipment status, and consumable capacity, supporting remote monitoring and alarms. Additionally, the data traceability and management system records key parameters such as pH adjustment logs, liquid volume, and ultrasonic time. Data can be exported and seamlessly integrated with LIMS (Laboratory Information Management System). The system can automatically schedule tasks based on recipe priorities, preparing 140L of mobile phase within 24 hours, with efficiency improvements of 300% compared to manual operations.

2. Technological Innovation: From Manual to Fully Automated

Compared to traditional manual preparation methods, Dark Laboratory's solution achieves a leap from manual to fully automated operations through three major technological innovations.

Precision Liquid Addition and pH Control  The workstation uses high-precision injection pumps (error < 0.5%) and real-time pH meters. The robot automatically adjusts the amount of acid or alkali added based on preset values, ensuring solvent system stability.

Fully Automated Powder Weighing  The introduction of top-loading weighing technology enables automatic powder packaging, effectively avoiding contamination caused by manual handling and reducing the cost per sample by 90%.

Closed-loop Safety Design  The workstation is equipped with visible windows and safety automatic doors on all sides. If personnel intervene, the equipment will automatically stop; if the AGV is not in place, the robot will cease operations to prevent collisions.

3. Application Scenarios and Industry Case

Dark Laboratory's mobile phase preparation workstation shows broad application prospects in fields such as pharmaceuticals, food testing, and chemical research.

Pharmaceutical Industry  The workstation, in conjunction with HPLC, enables the automated preparation and transfer of dissolution solutions and mobile phases, supporting continuous batch production with a daily sample processing capacity of up to 140 liters.

Food Testing Field  The system can quickly switch between different solvent formulations and ensure chromatographic peak stability through ultrasonic degassing, providing strong support for pesticide residue analysis.

Chemical Research Field  The workstation supports a many-to-many distribution mode, providing customized solvents for multiple reactors simultaneously, significantly accelerating high-throughput experiments.

4. Maintenance and Upgrades: Intelligent Guarantees for Long-Term Operation

To ensure the long-term stable operation of the workstation, Dark Laboratory also provides intelligent maintenance and upgrade solutions.

Self-Cleaning and Preemptive Maintenance  The injection pump automatically flushes the pipeline each time it starts, with waste liquid collected centrally; the software monitors consumables (such as filter membranes and acid-base reagents) in real time and replaces them promptly.

Modular Design Key components such as ultrasonic devices and pH meters can be independently disassembled and repaired, effectively reducing downtime.

Remote Support Through cloud-based diagnostic systems, technicians can remotely analyze fault logs and provide solutions, reducing response time to 2 hours.

5. Future Trends: Dual Upgrades in Intelligence and Sustainability

Looking ahead, Dark Laboratory's mobile phase preparation technology will develop in the direction of greater intelligence and sustainability.

AI-Driven Formulation Optimization By integrating machine learning algorithms, the system can predict the optimal solvent ratio based on historical data, thereby reducing trial-and-error costs and improving experimental efficiency.

Cross-Platform Collaboration  Through deep integration with AGVs and automated analytical instruments (such as mass spectrometers), an "unmanned laboratory" ecosystem is constructed, achieving a higher degree of automation and intelligence.

Green Upgrades  By introducing a waste liquid recovery module, used mobile phases are purified and recycled, not only reducing environmental pressure but also achieving sustainable resource utilization.

Dark Laboratory's automated mobile phase technology is not only an improvement in experimental efficiency but also a paradigm shift for laboratories. Dynaflow's solution, through the deep integration of hardware, software, and data, provides replicable mobile phase preparation solutions for industries such as pharmaceuticals and chemicals. In the future, with continuous technological advancements and expanded applications, laboratories will completely move beyond the limitations of manual operations and enter a new era of full-process intelligence and sustainable development.